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Image Search Results
Journal: Journal of the American Society of Nephrology : JASN
Article Title: C1-Inhibitor Decreases the Release of Vasculitis-Like Chemotactic Endothelial Microvesicles
doi: 10.1681/ASN.2016060637
Figure Lengend Snippet: EMVs in vasculitis plasma express B1R. Plasma samples from patients with vasculitis (n=12, patients 1–7 and 9–13 in Table 1) and healthy controls (n=15) exhibited significantly higher levels of EMVs, positive for CD105 and/or CD144. Circulating EMVs were B1R-positive and samples from patients with vasculitis had significantly higher levels of B1R compared with controls. Samples were run using a BD FACSCanto Cytometer. ***P<0.001.
Article Snippet: Flow cytometry was performed using a
Techniques: Cytometry
Journal: Journal of the American Society of Nephrology : JASN
Article Title: C1-Inhibitor Decreases the Release of Vasculitis-Like Chemotactic Endothelial Microvesicles
doi: 10.1681/ASN.2016060637
Figure Lengend Snippet: B1R is found on EMVs released after perfusion of PGECs. (A) Plasma samples from patients with vasculitis (n=6) and healthy controls (n=6) perfused over PGECs at a shear stress of 2 dynes/cm2 for 15 minutes induced the release of EMVs (CD144-positive and CD105-positive MVs). Patient plasma samples contained more EMVs than control samples before perfusion (presample). Perfused plasma samples from patients with vasculitis exhibited significantly higher levels of EMVs than controls. (B) Patient samples contained more B1R-positive EMVs before perfusion (presample). Perfused samples from patients with vasculitis had significantly higher levels of B1R-positive EMVs compared with controls (the lowest value of B1R-positive EMVs in control plasma was 0.03×106/ml). Statistical comparisons were carried out between patients and controls, but not between presamples and perfused samples. Samples were analyzed using a BD FACSCanto Cytometer. **P<0.01; *P<0.05.
Article Snippet: Flow cytometry was performed using a
Techniques: Cytometry